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KMID : 0914820090090040238
Journal of the Korean Gastric Cancer Association
2009 Volume.9 No. 4 p.238 ~ p.245
Factors Affecting Prognosis in Early Gastric Cancer
Han Ki-Bin

Jang You-Jin
Kim Jong-Han
Park Sung-Soo
Park Sung-Heum
Kim Seung-Joo
Mok Young-Jae
Kim Chong-Suk
Abstract
Purpose: Treatment strategies for early gastric carcinoma (EGC) should be based on achieving a complete cure, but clear indications for limited surgery have not been established. We investigated surgical outcomes for early gastric cancer to determine the optimal? treatment strategy for EGC.

Materials and Methods : Subjects included 881 patients who underwent curative surgery for EGC between 1986 and 2003. Retrospective uni & multi-variate analysis for prognostic factors, factors affecting lymph node metastasis, and risk factors for cancer recurrence were analyzed.

Results: In multivariate survival analyses, age, operation method, macroscopic appearance and lymph node stage proved to be independent prognostic factors. Lymph node metastasis, depth of tumor invasion, tumor size, lymphatic and venous invasion were also significant risk factors in multivariate analyses. In multivariate analyses for cancer recurrence, depth of tumor invasion and lymph node metastasis proved to be significant risk factors.

Conclusion: Appropriate surgical treatment with lymph node dissection is necessary for EGC patients with risk factors for lymph node metastasis.
KEYWORD
Early gastric cancer, Prognostic factors, Lymph node metastasis
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